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TReaDS: Tandem Repeats Discovery ServiceAlessio Vecchio1, M. Elena Renda2 and Marco Pellegrini2 Istituto di Informatica e Telematica - C.N.R. Technical Report
Number: 2008-TR-06 1 Dipartimento di Ingegneria dell'Informazione 2 Istituto di Informatica e Telematica (IIT) Abstract. Tandem repeats (TRs) are multiple duplications of substrings in the DNA that occur contiguously, or at a short distance, and may involve some mutations (such as substitutions, insertions, and deletions). The analysis of TRs is an important genetic profiling technique. In fact, TRs can be used, for instance, to detect evolutionary phenomena in populations, to identify the cause of several diseases, and to help in determining parentage. There are several web-based resources or downloadable packages for finding TRs, but such tools rarely give exactly the same result for a given input. Thus, biologists could be interested in a tool that, not only gives them the possibility of querying multiple systems at the same time, but also simplifies the burden of comparing and merging the results. TReaDS (Tandem Repeats Discovery Service) is a tandem repeat meta search engine that finds exact, approximate, short and long TRs. TReaDS queries several web-based tools and merges their outcome into a single report, providing a global, synthetic, and comparative view of the different results. Availability TReaDS, the Tandem Repeats Discovery Service, is a web application free and open to all users without login requirement at the following URL: http://bioalgo.iit.cnr.it/treads. For full paper: please contact me (Elena.Renda_AT_iit.cnr.it).
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